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The world-leading research team at the University of Gothenburg has achieved a remarkable milestone. They have successfully conducted uterine transplantation surgeries utilizing cutting-edge robotic technology, both in the donor and the recipient. Then, a woman conceived through in vitro fertilization (IVF) and had a first childbirth ever after such a procedure.
A Groundbreaking Advancement in Global Transplantation Practice
A baby boy, measuring 19.3 inches in length and weighing 6 pounds 13 ounces, entered the world on May 25th via planned cesarean section. Both the newborn, his 35-year-old mother, and the generous donor, a relative of the mother, are in excellent health and spirits.
The donor and recipient underwent a groundbreaking procedure, entirely utilizing the robotic-assisted laparoscopic (keyhole) surgery, with no open-surgery stage.
This innovative approach is a considerably less invasive method than traditional open surgery. The risks of infections and bleeding are decreased, and there is faster recovery for the patients.
How the Transplantation Was Performed
The technique involves inserting cameras and robotic arms with attached surgical instruments through small incisions in the lower abdomen. Surgeons then manipulate the robotic arms using instrument controls similar to joysticks on consoles. They can simultaneously view mobile 3D images and work with high precision.
The transplantation was performed at Sahlgrenska University Hospital in October 2021. The donor’s uterus was gradually freed using a robotic surgeon. It was then detached from the blood vessels and removed vaginally in a laparoscopic pouch.
The recipient’s uterus was inserted through a small incision. First, it was stitched to the blood vessels, and then connected to the vagina and supporting tissue. All these steps were assisted by robot surgery.
The first childbirth and pregnancy following a robotic-assisted uterus transplantation
After ten months since the transplantation, a previously frozen embryo was implanted into the transplanted uterus using in vitro fertilization (IVF). Astonishingly, the pregnancy was confirmed within a few weeks. Throughout the entire pregnancy, the expectant mother experienced excellent health and delivered via planned C-section at 38 weeks.
With robot-assisted keyhole surgery, we can carry out ultra-fine precision surgery. The technique gives a very good access to operate deep down into the pelvis. This is the surgery of the future, and we’re proud and glad to have been able to develop uterine transplantations to this minimally invasive technical level.”
Pernilla Dahm-Kähler, adjunct professor of obstetrics and gynecology at Sahlgrenska Academy, University of Gothenburg
This groundbreaking achievement signifies a significant leap forward in the field of uterine transplantation surgery, which originally commenced with open surgery techniques in Sweden back in 2012. Leading the effort is Professor Mats Brännström, an obstetrics and gynecology specialist at the Sahlgrenska Academy, University of Gothenburg. Professor Brännström serves as both a renowned gynecologist and senior consultant at the university hospital.
This is the 14th baby born in the uterus transplantation project at Sahlgrenska Academy, and more births are awaited this summer. The research project continuously evaluates numerous variables in donors, recipients, and children after the uterus transplantation, following up the operation for several years afterward. All this is done to maximize the efficacy of the operation and minimize side effects in the patients
Mats Brännström, professor of obstetrics and gynecology at Sahlgrenska Academy, University of Gothenburg
It is worth noting that recent scientific advancements have also led to the development of electronic tattoos to fight against heart diseases.
